Small molecules which reverse POLG KO
Canned Analysis
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General Information
AccessionDCA00021704
TitleSmall molecules which reverse POLG KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by POLG KO in the bone marrow cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21d7ae467bea600fbae42
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2211
Cell Typebone marrow
Gene Symbol (human)POLG
Gene Symbol (mouse)Polg
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM685754, GSM685755, GSM685756
Perturbed SamplesGSM685751, GSM685752, GSM685753
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27686
Gene Expression Omnibus
Premature Hematopoietic Aging model: bone marrow hematopoietic stem cells
7
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