Small molecules which reverse IGH mutation (unspecified)
Canned Analysis
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General Information
AccessionDCA00021718
TitleSmall molecules which reverse IGH mutation (unspecified)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IGH mutation (unspecified) in the B cell lymphocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21d71e467bea600fbae3e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2216
Cell TypeB cell lymphocytes
Gene Symbol (human)IGH
Organismhuman
Perturbation Typemutation (unspecified)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM879118, GSM879119, GSM879120, GSM879121, GSM879122, GSM879125, GSM879126, GSM879127, GSM879129, GSM879140, GSM879147, GSM879148, GSM879154, GSM879155
Perturbed SamplesGSM879123, GSM879124, GSM879128, GSM879130, GSM879131, GSM879132, GSM879133, GSM879134, GSM879135, GSM879136, GSM879137, GSM879138, GSM879139, GSM879141, GSM879142, GSM879143, GSM879144, GSM879145, GSM879146, GSM879149, GSM879150, GSM879151, GSM879152, GS
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE36000
Gene Expression Omnibus
IGHV mutated/unmutated Mantle Cell Lymphoma patients: B cell lymphocytes
7
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