Small molecules which mimic SMC3 KD
Canned Analysis
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General Information
AccessionDCA00021723
TitleSmall molecules which mimic SMC3 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SMC3 KD in the MCF7 human breast cancer cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22da4e467bea600fbb560
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2222
Cell TypeMCF7 human breast cancer cell line
Gene Symbol (human)SMC3
Gene Symbol (mouse)Smc3
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM937477, GSM937478, GSM937479
Perturbed SamplesGSM937489, GSM937490, GSM937491
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE38252
Gene Expression Omnibus
Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene
28
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