Small molecules which mimic SMC3 KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021727
TitleSmall molecules which mimic SMC3 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SMC3 KD in the MCF7 + estrogen cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d215a2e467bea600fbaafc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorpdish
CREEDS IDgene:2862
Cell TypeMCF7 + estrogen
Gene Symbol (human)SMC3
Gene Symbol (mouse)Smc3
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM937480, GSM937481, GSM937482
Perturbed SamplesGSM937492, GSM937493, GSM937494
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38252
Gene Expression Omnibus
Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene
28
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.