Small molecules which reverse GATA6 KO
Canned Analysis
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General Information
AccessionDCA00021734
TitleSmall molecules which reverse GATA6 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GATA6 KO in the tissue resident peritoneal macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22d78e467bea600fbb54e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2225
Cell Typetissue resident peritoneal macrophages
Gene Symbol (human)GATA6
Gene Symbol (mouse)Gata6
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1143766, GSM1143767, GSM1143768
Perturbed SamplesGSM1143763, GSM1143764, GSM1143765
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47049
Gene Expression Omnibus
Expression data from wild type and Gata6-deficient tissue resident peritoneal macrophages
7
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