Small molecules which reverse INSM1 Deficiency
Canned Analysis
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General Information
AccessionDCA00021738
TitleSmall molecules which reverse INSM1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by INSM1 Deficiency in the Fetal pituitary glands from embryonic day 17.5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d226f9e467bea600fbb26a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:299
Cell TypeFetal pituitary glands from embryonic day 17.5
Gene Symbol (human)INSM1
Gene Symbol (mouse)Insm1
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1124857, GSM1124858, GSM1124859, GSM1124860, GSM1124861, GSM1124862, GSM1124863, GSM1124864, GSM1124865, GSM1124866
Perturbed SamplesGSM1124851, GSM1124852, GSM1124853, GSM1124854, GSM1124855, GSM1124856
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46139
Gene Expression Omnibus
Insm1 deficiency effect on the fetal pituitary gland
14
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