Small molecules which mimic HIF1A KD
Canned Analysis
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General Information
AccessionDCA00021745
TitleSmall molecules which mimic HIF1A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HIF1A KD in the Heptaocellular carcinoma cell line HepG2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d228a3e467bea600fbb328
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2234
Cell TypeHeptaocellular carcinoma cell line HepG2
Gene Symbol (human)HIF1A
Gene Symbol (mouse)Hif1a
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1094265, GSM1094266, GSM1094267
Perturbed SamplesGSM1094259, GSM1094260, GSM1094261
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44943
Gene Expression Omnibus
HIF-1 dependent gene expression upon S. aureus infection
14
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