Small molecules which mimic TIAM1 KD
Canned Analysis
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General Information
AccessionDCA00021749
TitleSmall molecules which mimic TIAM1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TIAM1 KD in the cell line: Y79 cell type: Retinoblastoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d204dae467bea600fba39c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2236
Cell Typecell line: Y79 cell type: Retinoblastoma
Gene Symbol (human)TIAM1
Gene Symbol (mouse)Tiam1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1097757, GSM1097759, GSM1097761
Perturbed SamplesGSM1097758, GSM1097760, GSM1097762
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE45130
Gene Expression Omnibus
Whole genome microarray of T lymphoma invasion and metastasis (Tiam1) silenced retinoblastoma Y79 cells
7
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