Small molecules which mimic HIRA KD
Canned Analysis
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General Information
AccessionDCA00021753
TitleSmall molecules which mimic HIRA KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HIRA KD in the cell type: HeLa cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d204a3e467bea600fba384
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2238
Cell Typecell type: HeLa
Gene Symbol (human)HIRA
Gene Symbol (mouse)Hira
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1101720, GSM1101721, GSM1101722
Perturbed SamplesGSM1101717, GSM1101718, GSM1101719
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE45295
Gene Expression Omnibus
Expression data from Control, HIRA and CABIN1 knockdown cells
14
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