Small molecules which reverse IKBKB KO
Canned Analysis
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General Information
AccessionDCA00021770
TitleSmall molecules which reverse IKBKB KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IKBKB KO in the non-small cell lung cancer nodules cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b48e467bea600fba672
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2246
Cell Typenon-small cell lung cancer nodules
Gene Symbol (human)IKBKB
Gene Symbol (mouse)Ikbkb
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM743883, GSM743884, GSM743889, GSM743890
Perturbed SamplesGSM743891, GSM743892, GSM743893, GSM743894
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30049
Gene Expression Omnibus
Expression data comparing the effect of IKK2 KO on a KRAS mouse model
14
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