Small molecules which mimic KRAS Knock-down, shRNA
Canned Analysis
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General Information
AccessionDCA00021771
TitleSmall molecules which mimic KRAS Knock-down, shRNA
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by KRAS Knock-down, shRNA in the LKR13 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b4ee467bea600fba674
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2247
Cell TypeLKR13
Gene Symbol (human)KRAS
Gene Symbol (mouse)Kras
Organismmouse
Perturbation TypeKnock-down, shRNA
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM384915, GSM384916, GSM384917, GSM384918
Perturbed SamplesGSM384911, GSM384912, GSM384919, GSM384920
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15326
Gene Expression Omnibus
LKR13-Kras-WT1-KO
14
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