Small molecules which reverse CTNNB1 KO
Canned Analysis
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General Information
AccessionDCA00021776
TitleSmall molecules which reverse CTNNB1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 KO in the liver tumor tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fc7fe467bea600fb9ff0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2249
Cell Typeliver tumor tissue
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1067299, GSM1067300, GSM1067301, GSM1067302
Perturbed SamplesGSM1067303, GSM1067304, GSM1067305, GSM1067306
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43628
Gene Expression Omnibus
Activation of beta-catenin in hepatocellular carcinoma (mouse Ctnnb1 knockout)
7
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