Small molecules which reverse PINK1 KO
Canned Analysis
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General Information
AccessionDCA00021804
TitleSmall molecules which reverse PINK1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PINK1 KO in the Midbrain - 6 weeks cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d216f0e467bea600fbab92
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curator
CREEDS ID
Cell Type
Gene Symbol (human)
Gene Symbol (mouse)
Organism
Perturbation Type
L1000CDS2 parameters
Direction
Characteristic Direction parameters
Control Samples
Perturbed Samples
Tools used in the analysis

Dataset Accession

L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis

Keyword
Tool Name

GSE60413
Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration
105
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