Small molecules which mimic PPP2R2D KD
Canned Analysis
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General Information
AccessionDCA00021847
TitleSmall molecules which mimic PPP2R2D KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PPP2R2D KD in the OT-I T cells from tumors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d234bbe467bea600fbb87e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDgene:2291
Cell TypeOT-I T cells from tumors
Gene Symbol (human)PPP2R2D
Gene Symbol (mouse)Ppp2r2d
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1290692, GSM1290693, GSM1290694
Perturbed SamplesGSM1290695, GSM1290696, GSM1290697
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE53388
Gene Expression Omnibus
Tumor-infiltrating CD8 T cells silenced for negative regulators of T cells
70
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