Small molecules which reverse HMGN5 Overexpression of mutated NSBP1SE protein which does not bind to
Canned Analysis
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General Information
AccessionDCA00021870
TitleSmall molecules which reverse HMGN5 Overexpression of mutated NSBP1SE protein which does not bind to
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HMGN5 Overexpression of mutated NSBP1SE protein which does not bind to in the clone type: AtT20 clone mouse pituitary gland cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d228ffe467bea600fbb352
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2300
Cell Typeclone type: AtT20 clone mouse pituitary gland cells
Gene Symbol (human)HMGN5
Organismmouse
Perturbation TypeOverexpression of mutated NSBP1SE protein which does not bind to
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM416605, GSM416606, GSM416607
Perturbed SamplesGSM416608, GSM416609, GSM416610
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16564
Gene Expression Omnibus
Expression data from AtT20 mouse pituitary gland cells following overexpression or down regulation of NSBP1
21
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