Small molecules which reverse MAPK7 constitutive activation
Canned Analysis
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General Information
AccessionDCA00021878
TitleSmall molecules which reverse MAPK7 constitutive activation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MAPK7 constitutive activation in the HUVEC cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d228dae467bea600fbb342
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorstevann
CREEDS IDgene:2307
Cell TypeHUVEC
Gene Symbol (human)MAPK7
Gene Symbol (mouse)Mapk7
Organismhuman
Perturbation Typeconstitutive activation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM448023, GSM448025, GSM448043
Perturbed SamplesGSM448029, GSM448041, GSM448047
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17939
Gene Expression Omnibus
Erk5 activation effect on endothelial cells
7
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