Small molecules which reverse PTEN KO
Canned Analysis
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General Information
AccessionDCA00021892
TitleSmall molecules which reverse PTEN KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PTEN KO in the Inner ear cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e4de467bea600fbae9e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorRuta
CREEDS IDgene:2321
Cell TypeInner ear
Gene Symbol (human)PTEN
Gene Symbol (mouse)Pten
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1201833, GSM1201834, GSM1201835
Perturbed SamplesGSM1201836, GSM1201837, GSM1201838
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49562
Gene Expression Omnibus
Exploring the gene expression associated with Pten deficiency in the developing inner ear
7
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