Small molecules which mimic AKT1 KO
Canned Analysis
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General Information
AccessionDCA00021901
TitleSmall molecules which mimic AKT1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by AKT1 KO in the mammary glands cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e6fe467bea600fbaeac
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2325
Cell Typemammary glands
Gene Symbol (human)AKT1
Gene Symbol (mouse)Akt1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM760658, GSM760662, GSM760663
Perturbed SamplesGSM760659, GSM760660, GSM760661
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30671
Gene Expression Omnibus
Comparison of Differences in Mouse Mammary gland gene expression data at POSTNATAL DAY 70 in Akt1wildtype versus Akt1-deficient mice
7
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