Small molecules which reverse ESR1 KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021904
TitleSmall molecules which reverse ESR1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ESR1 KD in the MCF7 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e8de467bea600fbaeba
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2326
Cell TypeMCF7
Gene Symbol (human)ESR1
Gene Symbol (mouse)Esr1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM928442, GSM928443, GSM928444
Perturbed SamplesGSM928445, GSM928446, GSM928447
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE37820
Gene Expression Omnibus
Gene expression profile in MCF7 breast cancer cells after siRNA knock down of estrogen receptor alpha (ESR1)
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.