Small molecules which reverse BPTF KO
Canned Analysis
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General Information
AccessionDCA00021906
TitleSmall molecules which reverse BPTF KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BPTF KO in the embryonic fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e0de467bea600fbae82
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorRuta
CREEDS IDgene:2328
Cell Typeembryonic fibroblasts
Gene Symbol (human)BPTF
Gene Symbol (mouse)Bptf
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1169021, GSM1169023, GSM1169024
Perturbed SamplesGSM1169020, GSM1169022, GSM1169025
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48123
Gene Expression Omnibus
Genome-wide measurement of gene expression changes with Bptf knockout in mouse embryonic fibroblasts
7
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