Small molecules which reverse MIR126 OE
Canned Analysis
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General Information
AccessionDCA00021916
TitleSmall molecules which reverse MIR126 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MIR126 OE in the source tissue: umbilical cord blood cell type: CD34+/CD38- Lin- cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22427e467bea600fbb12a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2334
Cell Typesource tissue: umbilical cord blood cell type: CD34+/CD38- Lin- cells
Gene Symbol (human)MIR126
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM994480, GSM994484, GSM994488
Perturbed SamplesGSM994481, GSM994485, GSM994489
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40458
Gene Expression Omnibus
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
14
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