Small molecules which reverse FTO KD
Canned Analysis
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General Information
AccessionDCA00021918
TitleSmall molecules which reverse FTO KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FTO KD in the Flp-Inâ???????¢ 293 T-Rex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22430e467bea600fbb12e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2335
Cell TypeFlp-Inâ???????¢ 293 T-Rex
Gene Symbol (human)FTO
Gene Symbol (mouse)Fto
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM838203, GSM838205
Perturbed SamplesGSM838202, GSM838204
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE33870
Gene Expression Omnibus
Effect of FTO overexpression and knockdown on transcriptome of HEK293 cells
21
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