Small molecules which mimic YAP1 KD
Canned Analysis
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General Information
AccessionDCA00021925
TitleSmall molecules which mimic YAP1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by YAP1 KD in the cell line: Hep3B cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2241be467bea600fbb124
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2337
Cell Typecell line: Hep3B
Gene Symbol (human)YAP1
Gene Symbol (mouse)Yap1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM860172, GSM860173, GSM860174
Perturbed SamplesGSM860178, GSM860179, GSM860180
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35004
Gene Expression Omnibus
YAP Inhibition in HCC cells (Hep3B)
7
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