Small molecules which mimic PRSS2 OE
Canned Analysis
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General Information
AccessionDCA00021931
TitleSmall molecules which mimic PRSS2 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PRSS2 OE in the cell line: HSC-3 cell type: human tongue squamous cell carcinoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ef8de467bea600fb9a86
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2340
Cell Typecell line: HSC-3 cell type: human tongue squamous cell carcinoma
Gene Symbol (human)PRSS2
Gene Symbol (mouse)Prss2
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM794751, GSM794752, GSM794753
Perturbed SamplesGSM794748, GSM794749, GSM794750
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE32056
Gene Expression Omnibus
The effect of trypsin-2 on human tongue squamous cell carcinoma cell line gene expression
7
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