Small molecules which reverse WNT1 OE
Canned Analysis
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General Information
AccessionDCA00021954
TitleSmall molecules which reverse WNT1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by WNT1 OE in the M24met melanoma cell-line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f4e3e467bea600fb9cd8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2356
Cell TypeM24met melanoma cell-line
Gene Symbol (human)WNT1
Gene Symbol (mouse)Wnt1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM656300, GSM656301, GSM656302, GSM656303, GSM656304
Perturbed SamplesGSM656305, GSM656306, GSM656307, GSM656308, GSM656309
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26656
Gene Expression Omnibus
Gene expression profiles of Wnt-1 overexpressing melanoma
14
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