Small molecules which reverse CHRNA9 KO
Canned Analysis
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General Information
AccessionDCA00021972
TitleSmall molecules which reverse CHRNA9 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CHRNA9 KO in the cochlea at P60 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23362e467bea600fbb7e4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDgene:2365
Cell Typecochlea at P60
Gene Symbol (human)CHRNA9
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM462025, GSM462026, GSM462027
Perturbed SamplesGSM462028, GSM462029, GSM462030
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE18567
Gene Expression Omnibus
Temporal profiling of gene expression in cochleae of wild type and alpha9 null mice
28
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