Small molecules which reverse TRAF3 KO
Canned Analysis
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General Information
AccessionDCA00021974
TitleSmall molecules which reverse TRAF3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TRAF3 KO in the spleen cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2337de467bea600fbb7f0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDgene:2366
Cell Typespleen
Gene Symbol (human)TRAF3
Gene Symbol (mouse)Traf3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1185228, GSM1185229, GSM1185230, GSM1185231
Perturbed SamplesGSM1185225, GSM1185226, GSM1185227
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48818
Gene Expression Omnibus
B lymphoma from TRAF3-deficient mice
7
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