Small molecules which reverse VAX2 KO
Canned Analysis
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General Information
AccessionDCA00021984
TitleSmall molecules which reverse VAX2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by VAX2 KO in the eyes at P60 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23902e467bea600fbba62
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDgene:2371
Cell Typeeyes at P60
Gene Symbol (human)VAX2
Gene Symbol (mouse)Vax2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM489385, GSM489386
Perturbed SamplesGSM489387, GSM489388
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19626
Gene Expression Omnibus
Profiling gene expression in Vax2 knockout compared with wild type mice
35
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