Small molecules which reverse NR2E3 Ectopic expression - (NRL null retinas expressing NR2E3)
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022004
TitleSmall molecules which reverse NR2E3 Ectopic expression - (NRL null retinas expressing NR2E3)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NR2E3 Ectopic expression - (NRL null retinas expressing NR2E3) in the Nrl-/- retina ( NRL - neural retinal leucine zipper - NULL Retinas) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22629e467bea600fbb20e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2384
Cell TypeNrl-/- retina ( NRL - neural retinal leucine zipper - NULL Retinas)
Gene Symbol (human)NR2E3
Gene Symbol (mouse)Nr2e3
Organismmouse
Perturbation TypeEctopic expression - (NRL null retinas expressing NR2E3)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM92610, GSM92611, GSM92612, GSM92613
Perturbed SamplesGSM121242, GSM121249, GSM121315, GSM121316
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5338
Gene Expression Omnibus
Photoreceptor-specific nuclear receptor NR2E3 ectopic expression effect on NRL null retinas
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.