Small molecules which mimic RICTOR KO
Canned Analysis
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General Information
AccessionDCA00022017
TitleSmall molecules which mimic RICTOR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RICTOR KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b85e467bea600fba68c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorRuta
CREEDS IDgene:2392
Cell Typeliver
Gene Symbol (human)RICTOR
Gene Symbol (mouse)Rictor
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1131555, GSM1131556, GSM1131557, GSM1131558
Perturbed SamplesGSM1131559, GSM1131560, GSM1131561, GSM1131562
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46515
Gene Expression Omnibus
Expression data from mouse model using targeted deletion of hepatic RICTOR (Albumin-Cre Rictor LoxP/LoxP)
7
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