Small molecules which mimic RORA gene truncation
Canned Analysis
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General Information
AccessionDCA00022019
TitleSmall molecules which mimic RORA gene truncation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RORA gene truncation in the skeletal muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b8de467bea600fba690
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorstevann
CREEDS IDgene:2393
Cell Typeskeletal muscle
Gene Symbol (human)RORA
Gene Symbol (mouse)Rora
Organismmouse
Perturbation Typegene truncation
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM518351, GSM518352, GSM518353
Perturbed SamplesGSM518354, GSM518355, GSM518356
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20646
Gene Expression Omnibus
ROR alpha1 deletion effect on skeletal muscle
7
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