Small molecules which reverse RUNX1 KO
Canned Analysis
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General Information
AccessionDCA00022022
TitleSmall molecules which reverse RUNX1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RUNX1 KO in the Colons from genotype: Villin-Cre + OR Cre- / Runx1-floxed strain: C57BL/6 background cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b99e467bea600fba696
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2396
Cell TypeColons from genotype: Villin-Cre + OR Cre- / Runx1-floxed strain: C57BL/6 background
Gene Symbol (human)RUNX1
Gene Symbol (mouse)Runx1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM846857, GSM846861
Perturbed SamplesGSM846855, GSM846859
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34292
Gene Expression Omnibus
Runx1 is a tumor suppressor gene in the mouse gastrointestinal tract
7
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