Small molecules which mimic NR0B2 KO
Canned Analysis
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General Information
AccessionDCA00022023
TitleSmall molecules which mimic NR0B2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NR0B2 KO in the tissue: liver (SHP uncertain if it is NR0B2 or PTPN6) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b69e467bea600fba680
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2398
Cell Typetissue: liver (SHP uncertain if it is NR0B2 or PTPN6)
Gene Symbol (human)NR0B2
Gene Symbol (mouse)Nr0b2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1001306, GSM1001307
Perturbed SamplesGSM1001308, GSM1001309
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40775
Gene Expression Omnibus
Microarray analysis of genes regulated by SHP in wild-type and ob/ob mice.
7
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