Small molecules which reverse DICER1 KO
Canned Analysis
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General Information
AccessionDCA00022038
TitleSmall molecules which reverse DICER1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DICER1 KO in the tissue: uterine age: 15 days background: C57BL/6J;129S5/Brd mixed hybrid genotype/variation: Cre knockout of Dicer OR control cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20bcfe467bea600fba6ae
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2406
Cell Typetissue: uterine age: 15 days background: C57BL/6J;129S5/Brd mixed hybrid genotype/variation: Cre knockout of Dicer OR control
Gene Symbol (human)DICER1
Gene Symbol (mouse)Dicer1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM957628, GSM957629, GSM957631
Perturbed SamplesGSM957630, GSM957632
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39181
Gene Expression Omnibus
Gene expression profiling of mouse uterine tissue from progesterone receptor-Cre knockout of Dicer
7
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