Small molecules which reverse MIR122 KO
Canned Analysis
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General Information
AccessionDCA00022042
TitleSmall molecules which reverse MIR122 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MIR122 KO in the background strain: B6/129, tissue: liver/tumor cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20be1e467bea600fba6b6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2408
Cell Typebackground strain: B6/129, tissue: liver/tumor
Gene Symbol (human)MIR122
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM781673, GSM781674, GSM781675, GSM781676, GSM781677
Perturbed SamplesGSM781678, GSM781679, GSM781680, GSM781681, GSM781682, GSM781683, GSM781684, GSM781685
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31453
Gene Expression Omnibus
Genome-wide analysis of gene expression patterns in the liver tumors of mir-122 knockout mice
7
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