Small molecules which mimic MECP2 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022061
TitleSmall molecules which mimic MECP2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MECP2 KO in the brain, motor cortex, fast spiking interneurons cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20724e467bea600fba4a0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2414
Cell Typebrain, motor cortex, fast spiking interneurons
Gene Symbol (human)MECP2
Gene Symbol (mouse)Mecp2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM215857, GSM215858, GSM215859, GSM215860
Perturbed SamplesGSM215861, GSM215862, GSM215863, GSM215864
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8720
Gene Expression Omnibus
Cell type specific expression data from Mecp2 null mice
35
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.