Small molecules which reverse SST KO
Canned Analysis
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General Information
AccessionDCA00022080
TitleSmall molecules which reverse SST KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SST KO in the liver, female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20287e467bea600fba29a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2422
Cell Typeliver, female
Gene Symbol (human)SST
Gene Symbol (mouse)Sst
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1363209, GSM1363210, GSM1363214
Perturbed SamplesGSM1363218, GSM1363219, GSM1363220
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE56520
Gene Expression Omnibus
Effect of somatostatin knockout on sexually dimorphic hepatic gene expression
14
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