Small molecules which reverse MAPK1 INHIBITION (ERK inhibitor U0126)
Canned Analysis
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General Information
AccessionDCA00022094
TitleSmall molecules which reverse MAPK1 INHIBITION (ERK inhibitor U0126)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MAPK1 INHIBITION (ERK inhibitor U0126) in the NIH3T3 cells - 4 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2027ee467bea600fba296
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2429
Cell TypeNIH3T3 cells - 4 Hours
Gene Symbol (human)MAPK1
Gene Symbol (mouse)Mapk1
Organismmouse
Perturbation TypeINHIBITION (ERK inhibitor U0126)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM107391, GSM107392, GSM107393
Perturbed SamplesGSM107396, GSM107397
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4739
Gene Expression Omnibus
ERK MAP kinase inactivation during G0/G1 to S phase transition: time course
7
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