Small molecules which mimic ESR1 KO
Canned Analysis
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General Information
AccessionDCA00022095
TitleSmall molecules which mimic ESR1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ESR1 KO in the Aorta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fbd5e467bea600fb9fa6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2430
Cell TypeAorta
Gene Symbol (human)ESR1
Gene Symbol (mouse)Esr1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM238478, GSM238479, GSM238480, GSM238481, GSM238482
Perturbed SamplesGSM238488, GSM238489, GSM238490
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9371
Gene Expression Omnibus
Estrogen effect on estrogen receptors alpha and beta single knockouts: aorta
14
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