Small molecules which reverse ESR2 KO
Canned Analysis
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General Information
AccessionDCA00022098
TitleSmall molecules which reverse ESR2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ESR2 KO in the Aorta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fbcfe467bea600fb9fa4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2431
Cell TypeAorta
Gene Symbol (human)ESR2
Gene Symbol (mouse)Esr2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM238478, GSM238479, GSM238480, GSM238481, GSM238482
Perturbed SamplesGSM238494, GSM238495, GSM238496
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9371
Gene Expression Omnibus
Estrogen effect on estrogen receptors alpha and beta single knockouts: aorta
14
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