Small molecules which mimic PPARA OE
Canned Analysis
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General Information
AccessionDCA00022103
TitleSmall molecules which mimic PPARA OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PPARA OE in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fc0ce467bea600fb9fbe
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2436
Cell Typeheart
Gene Symbol (human)PPARA
Gene Symbol (mouse)Ppara
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM67362, GSM67363, GSM67364, GSM67365, GSM67366, GSM67367, GSM67368
Perturbed SamplesGSM67376, GSM67377, GSM67378, GSM67379, GSM67380, GSM67381, GSM67382
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3067
Gene Expression Omnibus
Dominant negative thyroid hormone receptor expression and PPARalpha activation effect on the heart
14
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