Small molecules which mimic MSI2 OE
Canned Analysis
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General Information
AccessionDCA00022113
TitleSmall molecules which mimic MSI2 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MSI2 OE in the Hematopoietic stem and progenitor cells (LineageLow, Sca1+, Kit+; LSK) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23694e467bea600fbb94e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2441
Cell TypeHematopoietic stem and progenitor cells (LineageLow, Sca1+, Kit+; LSK)
Gene Symbol (human)MSI2
Gene Symbol (mouse)Msi2
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM563199, GSM563200, GSM563201
Perturbed SamplesGSM563202, GSM563203
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22773
Gene Expression Omnibus
Musashi 2 regulates normal hematopoiesis and accelerates leukemogenesis (LK and MS12-inducible)
7
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