Small molecules which reverse RS1 KO
Canned Analysis
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General Information
AccessionDCA00022154
TitleSmall molecules which reverse RS1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RS1 KO in the retina cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d217f9e467bea600fbac0a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDgene:2461
Cell Typeretina
Gene Symbol (human)RS1
Gene Symbol (mouse)Rs1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM130322, GSM130323, GSM130324
Perturbed SamplesGSM130325, GSM130326, GSM130327
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5581
Gene Expression Omnibus
Retinoschisis model
12
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