Small molecules which mimic FMR1 KO
Canned Analysis
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General Information
AccessionDCA00022159
TitleSmall molecules which mimic FMR1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by FMR1 KO in the lymphoblastoid cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f598e467bea600fb9d26
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2469
Cell Typelymphoblastoid cells
Gene Symbol (human)FMR1
Gene Symbol (mouse)Fmr1
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM176601, GSM176602, GSM176604, GSM176605, GSM176607, GSM176608, GSM176609, GSM176610, GSM176612, GSM176613, GSM176614, GSM176615, GSM176617, GSM176618, GSM176619
Perturbed SamplesGSM176570, GSM176575, GSM176579, GSM176583, GSM176586, GSM176589, GSM176592, GSM176594
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7329
Gene Expression Omnibus
Autism, fragile X syndrome, and 15q11-q13 duplication: lymphoblastoid cells
33
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