Small molecules which reverse DGCR8 KO
Canned Analysis
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General Information
AccessionDCA00022170
TitleSmall molecules which reverse DGCR8 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DGCR8 KO in the retina, cone photoreceptors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2119ce467bea600fba93e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2474
Cell Typeretina, cone photoreceptors
Gene Symbol (human)DGCR8
Gene Symbol (mouse)Dgcr8
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1412527, GSM1412528
Perturbed SamplesGSM1412537, GSM1412538
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE58493
Gene Expression Omnibus
Expression data of wild type and C-DGCR8 KO cones at different timepoints [array]
35
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