Small molecules which mimic DGCR8 KO
Canned Analysis
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General Information
AccessionDCA00022173
TitleSmall molecules which mimic DGCR8 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DGCR8 KO in the retina, cone photoreceptors, postnatal day 50 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d211a2e467bea600fba940
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2477
Cell Typeretina, cone photoreceptors, postnatal day 50
Gene Symbol (human)DGCR8
Gene Symbol (mouse)Dgcr8
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1412531, GSM1412532
Perturbed SamplesGSM1412541, GSM1412542
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE58493
Gene Expression Omnibus
Expression data of wild type and C-DGCR8 KO cones at different timepoints [array]
35
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