Small molecules which mimic FOXO1 KO
Canned Analysis
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General Information
AccessionDCA00022213
TitleSmall molecules which mimic FOXO1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by FOXO1 KO in the ventromedial hypothalamus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20e9ee467bea600fba7f0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2493
Cell Typeventromedial hypothalamus
Gene Symbol (human)FOXO1
Gene Symbol (mouse)Foxo1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM906960, GSM906961, GSM906962
Perturbed SamplesGSM906957, GSM906958, GSM906959
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36948
Gene Expression Omnibus
Genome-wide analysis of transcription factor FoxO1-responsive gene expression in the ventromedial hypothalamus
7
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