Small molecules which reverse RPS6KA3 KO
Canned Analysis
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General Information
AccessionDCA00022230
TitleSmall molecules which reverse RPS6KA3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RPS6KA3 KO in the mandibular molars cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d218a8e467bea600fbac56
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2517
Cell Typemandibular molars
Gene Symbol (human)RPS6KA3
Gene Symbol (mouse)Rps6ka3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1236386, GSM1236387, GSM1236388, GSM1236389, GSM1236390, GSM1236391, GSM1236392, GSM1236393
Perturbed SamplesGSM1236394, GSM1236395, GSM1236396, GSM1236397, GSM1236398, GSM1236399, GSM1236400, GSM1236401
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51034
Gene Expression Omnibus
RSK2 is a modulator of craniofacial development
7
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