Small molecules which reverse HES1 KO
Canned Analysis
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General Information
AccessionDCA00022232
TitleSmall molecules which reverse HES1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HES1 KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21854e467bea600fbac32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2518
Cell Typeliver
Gene Symbol (human)HES1
Gene Symbol (mouse)Hes1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1259425, GSM1259426, GSM1259427
Perturbed SamplesGSM1259431, GSM1259432, GSM1259433
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52106
Gene Expression Omnibus
Hes1 and Liver Glucocorticoid Signaling
7
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