Small molecules which reverse CHSY1 KO
Canned Analysis
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General Information
AccessionDCA00022234
TitleSmall molecules which reverse CHSY1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CHSY1 KO in the embryo forelimbs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2185ee467bea600fbac36
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2519
Cell Typeembryo forelimbs
Gene Symbol (human)CHSY1
Gene Symbol (mouse)Chsy1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM736648, GSM736649, GSM736650, GSM736651, GSM736652, GSM736653, GSM736654, GSM736655, GSM736656
Perturbed SamplesGSM736657, GSM736658, GSM736659, GSM736660, GSM736661, GSM736662, GSM736663, GSM736664, GSM736665, GSM736666, GSM736667, GSM736668, GSM736669
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE29694
Gene Expression Omnibus
Compare gene expression patterns in Chsy-1 wt and ko mouse 13.5 days embryo forelimbs
7
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